Chithandizo chachikulu ndi mankhwala ndipo chimaphatikizapo mankhwala a corticosteroid, mankhwala opangidwa ndi cortisone. Mankhwalawa ndi othandiza kwambiri, amachepetsa kwambiri chiopsezo cha zovuta za mitsempha zomwe zimapangitsa kuti matendawa akhale ovuta kwambiri. Mankhwalawa amagwira ntchito chifukwa cortisone ndi mankhwala amphamvu kwambiri oletsa kutupa omwe amadziwika, ndipo matenda a Horton ndi matenda otupa. Pakatha sabata, kusintha kwayamba kale ndipo mkati mwa mwezi umodzi wa chithandizo, kutupa kumayendetsedwa bwino.

Mankhwala a antiplatelet amawonjezeredwa. Izi ndizomwe zimalepheretsa mapulateleti m'magazi kuti asaphatikizidwe ndikupangitsa kuti kutsekeka kutsekereza kuzungulira kwa mtsempha wamagazi.

Kuchiza ndi cortisone koyambirira kumakhala pamlingo wokweza, ndiye, kutupa kukawongoleredwa (kuchuluka kwa sedimentation kapena ESR kwabwerera mwakale), dokotala amachepetsa mlingo wa corticosteroids pang'onopang'ono. Amafuna kupeza mlingo wochepa wothandiza kuti achepetse zotsatira zosafunika za mankhwalawa. Pafupifupi, chithandizo chimatenga zaka 2 mpaka 3, koma nthawi zina ndizotheka kuyimitsa cortisone posachedwa.

Chifukwa cha zovuta zomwe mankhwalawa angayambitse, anthu omwe akulandira chithandizo ayenera kuyang'anitsitsa panthawi ya chithandizo. Chisamaliro chapadera chiyenera kuperekedwa kwa okalamba kuti kupewa kuwonjezeka kwa kuthamanga kwa magazi (oopsa), A kufooka kwa mafupa (matenda a fupa) kapena matenda a maso (glaucoma, cataract).

Chifukwa cha zovuta zomwe zimagwirizanitsidwa ndi mankhwala a corticosteroid, njira zina zikuphunziridwa monga methotrexate, azathioprine, antimalarials synthetic, cyclosporin, ndi anti-TNF α, koma sizinawonetse mphamvu zapamwamba.