Mfundo zisanu zokhudzana ndi mankhwala osokoneza bongo

Kudya mopambanitsa sikutchedwa matenda a dziko lodyetsedwa bwino pachabe. Moyo wamakono umangothandizira kukulitsa chizolowezi ichi. Chakudya chamadzulo sabata yonse yogwira ntchito. Maphwando achikondwerero okhala ndi zakudya zambiri zovulaza. Kuwonera makanema apabanja masangweji ndi zokhwasula-khwasula. Mtengo wokondweretsa kwakanthawi kochepa kwa zokometsera zokometsera nthawi zambiri zimakhala zosasangalatsa zizindikiro za kudya mopitirira muyeso: kulemera mutatha kudya, kupweteka m'mimba, kuphulika, kuphulika. Ndipo, ngati thupi silipirira, mankhwala ochepetsa chimbudzi amathandizira. Kodi zimagwira ntchito bwanji? Kodi zonsezi ndi zothandiza? Ndani ayenera kuwatenga ndipo liti?

Mfundo # 1. Ma enzymes ndi ofunikira kuti chimbudzi chikhale bwino

Zimadziwika kuti kumverera kwa satiety kumabwera pang'onopang'ono. Pamene m'mimba mwadzaza ndi chakudya, timadzi ta satiety leptin timayamba kupangidwa. Zimakhudza mitsempha ya m'mimba, ndipo chizindikiro chimatumizidwa ku ubongo kuti thupi ladzaza. Pafupifupi, ndondomekoyi imatenga mphindi 30¹. Izi ndi zokwanira kuti mukhale ndi nthawi yodzaza mimba yanu ndi zakudya zowonjezera.

Kuchulukirachulukira kumadzipangitsa kumva ndi zomverera zosiyanasiyana. Timazunzidwa ndi kulemera m'mimba, kutupa, kusapeza bwino. Izi ndichifukwa choti palibe michere yokwanira m'mimba yopangidwa ndi kapamba, chifukwa kuchuluka kwa chakudya ndikwambiri.

Pankhaniyi, pamafunika zowonjezera. Ntchito yawo imatengedwa ndi mankhwala kuti apititse patsogolo chimbudzi, kapena kukonzekera kwa enzyme. Amapereka ma enzyme ofunikira omwe amakonza chakudya ndikuthandizira kuyamwa moyenera kwa michere.

Potsutsana ndi zakudya zosayenera, zosakhazikika, mavuto aakulu angabwere. Mwachitsanzo, kutentha kwa mtima, nseru, kutsegula m'mimba, kupweteka kwa m'mimba. Choncho, dongosolo lonse la m'mimba limavutika.

Mfundo # 2. Ma enzymes amafunikira pa chakudya chilichonse, mosasamala kanthu za kuchuluka kwake

Pancreas amapanga ma enzymes pa chakudya chilichonse, ngakhale titadya pang'ono. Panthawi imodzimodziyo, ili ndi enzyme yake yomwe imakonzekera mtundu uliwonse wa zakudya. Chifukwa chake, lipase imaphwanya mafuta, protease imathandizira kugaya mapuloteni, amylase amasintha ma carbohydrate ovuta kukhala osavuta.

Ngati kulemera ndi kusamva bwino kumachitika nthawi ndi nthawi mutatha kudya, izi zitha kuwonetsa kuti palibe michere yokwanira yopangidwa ndi kapamba. Pakhoza kukhala zifukwa zambiri: zakudya zosayenera, kusinthasintha kwa chilakolako, kusintha kwa msinkhu, kulephera kwa mahomoni, matenda opatsirana.

Ichi ndichifukwa chake kapamba amafunikira othandizira mwanjira yokonzekera ma enzyme. Ndikofunika kuzindikira kuti samachepetsa zokolola zake^{zonse 2}, zomwe zimakupatsani mwayi wokonza chakudya moyenera komanso moyenera. Ndipo popeza amalowa m’malo mwa ma enzyme a m’thupi, ayenera kuchita ndi chakudya ngati kuti anapangidwa okha.

Mfundo # 3. Ma enzyme amagwira ntchito m'matumbo, osati m'mimba

Tonse timakumbukira kuti chimbudzi chimayamba titangotumiza chakudya choyamba mkamwa mwathu. Malovu amakhala ndi ma enzymes omwe amayamba kugaya chakudya, kufewetsa chakudya ndikuthandizira kupitilira kummero. M'mimba imayambanso kutulutsa madzi am'mimba kuti azigawa chakudya.

Koma kugawanika kwakukulu kwa chakudya sikuchitika m'mimba, koma pambuyo pake - pamene imalowa m'matumbo. Panthawi imodzimodziyo, zakudya zomwezo zimapangidwira kuti thupi liyenera kukhala ndi nthawi yokwanira mokwanira. Ngati pali kulemera kapena kusapeza mutatha kudya, kukonzekera kwa enzyme kungagwiritsidwe ntchito pano. Koma si onse omwe amatha kufika m'matumbo nthawi imodzi ndi chakudya kapena amalowetsedwa pang'onopang'ono. Ndiye thupi limataya gawo lowoneka la "mafuta", choncho kulemera ndi kusapeza mutatha kudya kumatha kwa nthawi ndithu.

Pankhani imeneyi, puloteni kukonzekera Creon^® 10000 ikhoza kukhala wothandizira wokhulupirika. Imalowa m'matumbo nthawi imodzi ndi chakudya ndipo imayendetsedwa pakatha mphindi 15, ndikuchotsa kulemera pambuyo pakudya, kusapeza bwino m'mimba, kutupa, kupangika kwa gasi ndi zina zosasangalatsa.^.3 Koma chofunika kwambiri, zakudyazo zimatengedwa moyenera komanso moyenera. 

Mfundo # 4. Ma minimicrospheres ndi mawonekedwe amakono kwambiri a michere⁴

Zokonzekera zambiri za enzyme zimakhala ndi chinthu chimodzi chogwira ntchito - pancreatin. Kapangidwe ka ma enzymes ake kumagwirizana kwathunthu ndi omwe amapangidwa ndi kapamba. Chinyengo chagona pa mfundo yakuti si mankhwala onse amatha kupereka mankhwala yogwira ndendende mmene ankafunira - m`matumbo.

Mitundu yodziwika bwino ya ma enzymes ndi mapiritsi ndi ma dragees. Koma iwo ali ndi drawback kwambiri. Chifukwa cha mawonekedwe onse, mapiritsi sangathe kusakaniza mofanana ndi chakudya m'mimba ndikudutsa m'matumbo ndi gawo lililonse. N’chifukwa chake gawo limodzi lokha la nyamalo limalowa m’matumbo pamodzi ndi chakudya, chimene sichingakwanitse kugayidwa kwa chilichonse chodyedwa. Nthawi yomweyo, ma enzymes ena amatha kukhazikika m'mimba, ndipo tapeza kale kuti kukonzekera kwa ma enzyme kumakhala kopanda ntchito m'mimba. Kuonjezera apo, mapiritsi angakhale ovuta kumeza, makamaka kwa ana aang'ono ndi okalamba. Kuyesera kuwaphwanya kapena kuwapera kudzakhala kulakwitsa, chifukwa izi zidzawononga chipolopolo chotetezera cha piritsi, ndipo chilengedwe cha acidic cha m'mimba chidzawononga ma enzyme.

Chinthu chinanso ndi makapisozi "anzeru" a digestion Creon^®. Kapisozi iliyonse yotereyi imakhala ndi mazana a tinthu tating'onoting'ono, tokhala ndi mainchesi pafupifupi 1.15.^mm3. Ma minimicrospheres oterowo ndi ovomerezeka ndipo amapezeka kokha mu Creon yokonzekera^®5. Zimawonetsedwa kuti tinthu tating'onoting'ono ta enzyme, mankhwalawa ndi othandiza kwambiri^{3 akhoza kugwira ntchito}.

Mwa mawonekedwe awa, amasakanikirana bwino ndi chakudya m'mimba ndipo nthawi yomweyo amadutsa m'matumbo. Chofunika kwambiri, kuwonjezera pa kapisozi, minimicrosphere iliyonse imatetezedwa ndi chipolopolo chosamva asidi. Zimawathandiza kuti "apulumuke" m'malo am'mimba am'mimba ndikupereka ma enzyme ochulukirapo m'matumbo.³. Chifukwa cha njirayi, kutenga Creon^® kumathandiza chimbudzi kukhala chachilengedwe momwe kungathekere, zomwe zimatsimikizira chimbudzi chathunthu cha chakudya ndikutengera zakudya zonse.^.3

Mfundo # 5. Kusowa kwa michere kumakhudza thupi lonse

Kuperewera kwa michere kumakhudza thupi lonse⁶. Kudya mopambanitsa kumawononganso machitidwe ena a thupi. Kudzaza ndi chakudya chopitirira muyeso, mimba momvera imatambasula makoma ndikuwonjezeka kukula kwake. Chifukwa chake zimatha kuyika ziwalo za pachifuwa, ndulu, matumbo ndikusokoneza ntchito yawo yonse.

M’kupita kwa nthaŵi, kudya mopitirira muyeso kungayambitse kunenepa kwambiri⁶. Mapaundi owonjezera amapereka katundu wowonjezera pamtima⁶. Kupatula apo, iye, monga mpope wamphamvu, amayenera kupopa magazi m'njira yayitali.

Kudya mopambanitsa komanso kunenepa kwambiri kungayambitse kusokonezeka kwa metabolic⁷. Mafupa ndi msana zimakhala ndi katundu wambiri. Kusintha koopsa kwambiri kumachitika m'chiwindi. Ndipotu, minofu ya chiwindi imasanduka mafuta pang'onopang'ono⁷. Matenda a shuga ndi kusowa tulo nthawi zambiri zimatha⁸.

Kuti thupi lizigaya chakudya, limafunika kukonzekera ma enzyme. Amathandizira kukhazikitsa njira za kugaya ndi kagayidwe, zomwe zimathandiza kuti ntchito yolumikizana bwino ya ziwalo zina ndi machitidwe.

Kwa zizindikiro za kudya kwambiri, makapisozi 1-2 a Creon^® 10000 ndi yokwanira - ichi ndiye mulingo woyenera kwambiri wa michere yomwe imathandizira chimbudzi. Mutha kutenga Creon^® kwa aliyense ndipo pa msinkhu uliwonse, ngakhale amayi apakati ndi ana aang'ono kuyambira kubadwa⁹. Ndi bwino kuchita izi panthawi ya chakudya kapena mwamsanga, ndi madzi ochepa⁹.

Pazifukwa zina, thupi nthawi zambiri limasowa michere yawoyawo m'mimba. Njira yofulumira kwambiri yopangira kusowa kwawo ndikuthandizira kukonzekera kwa enzyme. Nthawi yomweyo, ndikofunikira kuti azigwira ntchito mwachangu, moyenera komanso moyenera momwe angathere. Ichi ndiye chinsinsi cha chimbudzi chokwanira komanso kutulutsa bwino kwa zinthu zothandiza. Ndipo pamodzi ndi iwo - thanzi labwino ndi thanzi la thupi lonse lonse.

1. Poltyrev SS Physiology ya chimbudzi: buku. buku. - Moscow: Sukulu Yapamwamba, 2003. - p. 386.

2. Belmer SV, Gasilina TV Digestive kusakwanira kwa kapamba mwa ana. Njira zosiyana// Khansara ya m'mawere, Amayi ndi Mwana. Pediatrics, 2007. - No. 1. 

3. Löhr JM, Hummel FM, Pirilis KT et al. Katundu wa mankhwala osiyanasiyana a pancreatin omwe amagwiritsidwa ntchito mu pancreatic exocrine insufficiency // Eur J Gastroenterol Hepatol., 2009; 21 (9): 1024–31.

4. Gubergrits NB, Kukulitsa luso lachirengedwe la enzyme kukonzekera: kupita patsogolo kuchokera pamapiritsi kupita ku minimicrosferon, "RMZH" No. 24 ya 19.12.2004, p. 1395.

5. Mankhwala okhawo a pancreatin mu mawonekedwe a minimicrospheres olembetsedwa m'gawo la Russian Federation, malinga ndi State Register of Legal Entities kuyambira 05.04.2019 / Source http://www.freepatent.ru/images/patents/52 /2408257/patent-2408257.pdf RU 2 408 364 C2 kulowa kuchokera 17.04.2019 ndi http://www.freepatent.ru/images/patents/18/2440101/patent-2440101.pdf 2 C440 RU 101 RU 2. .17.04.2019.

6. Lyubimova ZV Matenda a m'mimba. Njira zochiritsira zogwira mtima. – Moscow: Eksmo, 2009. – p. 117.

7. Trofimov S. Ya. Chimbudzi cha m'mimba. Matenda a m'mimba. - M .: Prosveshchenie, 2005. - p. 201.

8. Yakovlev MV Normal thunthu la munthu: nkhani zolemba. - Moscow: Sukulu Yapamwamba, 2003. - p. 312.

9. Malangizo ogwiritsira ntchito mankhwala a Creon® 10000 kuchokera ku 11.05.2018.

Nkhaniyi idapangidwa mothandizidwa ndi a Abbott Company kuti awonjezere chidziwitso cha odwala pazaumoyo.

RUCRE191033 kuyambira 17.04.2019