Asayansi apeza umboni wosonyeza kuti kusinkhasinkha kumayenderana ndi kuchuluka kwa nthawi ya moyo komanso kupititsa patsogolo chidziwitso mu ukalamba.
Mwinamwake mwamvapo kangapo za zotsatira zabwino zambiri zomwe machitidwe osinkhasinkha angabweretse. Mwinanso werengani m'nkhani zanga pamutuwu. Mwachitsanzo, kafukufuku watsopano akusonyeza kuti kusinkhasinkha kungachepetse kupsinjika maganizo ndi nkhawa, kuchepetsa kuthamanga kwa magazi, komanso kukupangitsani kukhala osangalala.
Zinapezeka kuti kusinkhasinkha kungathe kuchita zambiri: kungathandize kuchepetsa ukalamba ndikuwongolera khalidwe lachidziwitso mu ukalamba. Kodi izi zingatheke bwanji?
- Chepetsani kukalamba kwa ma cell
Kusinkhasinkha kumakhudza thupi lathu m'njira zosiyanasiyana, kuyambira pamlingo wa ma cell. Asayansi amasiyanitsa kutalika kwa telomere ndi mlingo wa telomerase monga zizindikiro za ukalamba wa maselo.
Maselo athu amakhala ndi ma chromosome, kapena kuti DNA. Ma telomeres ndi mapuloteni oteteza "zipewa" kumapeto kwa chingwe cha DNA zomwe zimapanga mikhalidwe yowonjezereka kwa maselo. Ma telomere akatalika, m'pamenenso selo limatha kugawikana ndi kudzipanganso. Nthawi iliyonse maselo akachulukana, kutalika kwa telomere - motero moyo wake - umafupika. Telomerase ndi puloteni yomwe imalepheretsa kufupikitsa telomere ndikuwonjezera moyo wa maselo.
Kodi zimenezi zikufanana bwanji ndi utali wa moyo wa munthu? Chowonadi ndi chakuti kufupikitsa kutalika kwa telomere m'maselo kumalumikizidwa ndi kuwonongeka kwa chitetezo chamthupi, kukula kwa matenda amtima ndi matenda osokonekera monga osteoporosis ndi matenda a Alzheimer's. Utali wa telomere ukakhala wamfupi, m’pamenenso maselo athu amafa kwambiri, ndipo timakhala otengeka kwambiri ndi matenda tikamakalamba.
Kufupikitsa kwa telomere kumachitika mwachibadwa pamene tikukalamba, koma kafukufuku wamakono akusonyeza kuti njirayi ikhoza kufulumizitsidwa ndi kupsinjika maganizo.
Kuchita mwanzeru kumayenderana ndi kuchepetsa kuganiza mosasamala komanso kupsinjika maganizo, kotero mu 2009 gulu lina lofufuza linanena kuti kusinkhasinkha kungakhale ndi zotsatira zabwino pa kusunga kutalika kwa telomere ndi ma telomerase.
Mu 2013, Elizabeth Hodge, MD, pulofesa wa psychiatry ku Harvard Medical School, adayesa lingaliro ili poyerekezera kutalika kwa telomere pakati pa osinkhasinkha mwachikondi (kusinkhasinkha kwa metta) ndi omwe satero. Zotsatira zake zidawonetsa kuti odziwa kusinkhasinkha kwa metta nthawi zambiri amakhala ndi ma telomere ataliatali, ndipo azimayi omwe amasinkhasinkha amakhala ndi ma telomere otalikirapo poyerekeza ndi azimayi osasinkhasinkha.
- Kusungidwa kwa voliyumu ya imvi ndi yoyera mu ubongo
Njira inanso yosinkhasinkha ingathandizire kukalamba pang'onopang'ono ndi kudzera mu ubongo. Makamaka, buku la imvi ndi woyera nkhani. Imvi imapangidwa ndi ma cell a ubongo ndi ma dendrite omwe amatumiza ndikulandila ma synapses kuti atithandize kuganiza ndi kugwira ntchito. Zinthu zoyera zimapangidwa ndi ma axon omwe amanyamula zizindikiro zenizeni zamagetsi pakati pa ma dendrites. Nthawi zambiri, kuchuluka kwa imvi kumayamba kuchepa ali ndi zaka 30 pamitengo yosiyana komanso m'malo osiyanasiyana, kutengera mawonekedwe amunthu. Panthawi imodzimodziyo, timayamba kutaya voliyumu ya nkhani yoyera.
Kafufuzidwe kakang'ono koma komwe kakukula kakuwonetsa kuti kudzera mu kusinkhasinkha timatha kukonzanso ubongo wathu ndikuchepetsa kuwonongeka kwamapangidwe.
Mu kafukufuku wa Massachusetts General Hospital mogwirizana ndi Harvard Medical School mu 2000, asayansi ntchito maginito resonance imaging (MRI) kuyeza makulidwe a cortical imvi ndi woyera nkhani ubongo mu osinkhasinkha ndi osasinkhasinkha mibadwo yosiyana. Zotsatirazo zinasonyeza kuti pafupifupi makulidwe a cortical mwa anthu azaka zapakati pa 40 ndi 50 omwe amasinkhasinkha amafanana ndi osinkhasinkha ndi osasinkhasinkha azaka zapakati pa 20 ndi 30. Kuchita kusinkhasinkha pa nthawi ino ya moyo kumathandiza kusunga kapangidwe ka ubongo pakapita nthawi.
Zotsatirazi ndi zofunika kwambiri moti asayansi ayamba kufufuza zambiri. Mafunso omwe akuyembekezera mayankho asayansi ndi kangati komwe kuli koyenera kusinkhasinkha kuti mukhale ndi zotsatira zotere, komanso ndi mitundu iti ya kusinkhasinkha yomwe imakhudza kwambiri ukalamba, makamaka kupewa matenda osokonekera monga matenda a Alzheimer's.
Tidazolowera lingaliro lakuti ziwalo zathu ndi ubongo m'kupita kwa nthawi zimatsatira njira yodziwika bwino ya chitukuko ndi kuwonongeka, koma umboni watsopano wa sayansi umasonyeza kuti kupyolera mu kusinkhasinkha timatha kuteteza maselo athu ku ukalamba msanga ndikukhalabe ndi thanzi mu ukalamba.