Hyperlymphocytosis ndi kuwonjezeka kwachilendo kwa ma lymphocyte m'magazi. Zitha kukhala pachimake pamene anakumana pa matenda tizilombo kapena aakulu, makamaka pamene kugwirizana ndi zilonda hemopathy. Hyperlymphocytosis imapezeka panthawi yoyezetsa magazi osiyanasiyana. Ndipo chithandizo chimadalira chifukwa chake.

Tanthauzo

Hyperlymphocytosis ndi kuwonjezeka kwachilendo kwa chiwerengero cha lymphocytes m'magazi nthawi zambiri zosakwana 4000 lymphocytes pa cubic millimeter mwa akulu.

Lymphocyte ndi leukocyte (mwa kuyankhula kwina maselo oyera a magazi) omwe amagwira ntchito yofunika kwambiri pa chitetezo cha mthupi. Pali mitundu itatu ya ma lymphocyte:

• Ma lymphocyte B: akakumana ndi antigen, amatulutsa ma antibodies ku chinthu chachilendo m'thupi
• T lymphocyte: Ena amawononga ma antigen ndi ma cell omwe ali ndi kachilombo pomangirira ku nembanemba ya maselo awo kuti awabaye ndi michere yapoizoni, ena amathandiza ma B lymphocyte kupanga ma antibodies, ndipo ena amapanga zinthu zoletsa chitetezo cha mthupi.
• Natural Killer lymphocytes: ali ndi zochitika zachilengedwe za cytotoxic zomwe zimawalola kuwononga ma cell omwe ali ndi ma virus kapena ma cell a khansa.

mitundu

Hyperlymphocytosis ikhoza kukhala:

• pachimake pamene anakumana ndi tizilombo matenda;
• Matenda (opitirira miyezi iwiri) makamaka pamene akugwirizana ndi matenda oopsa a hemopathy;

Zimayambitsa

Pachimake (kapena reactive) hyperlymphocytosis ikhoza kuyambitsidwa ndi:

• Matenda a virus (mumps, nkhuku kapena mononucleosis, hepatitis, rubella, kachilombo ka HIV, matenda a Carl Smith);
• Matenda ena oyambitsidwa ndi mabakiteriya, monga chifuwa chachikulu kapena chifuwa chachikulu, amatha kukhala ndi zotsatira zofanana;
• Kumwa mankhwala enaake;
• Katemera;
• Matenda a endocrine;
• Matenda a Autoimmune;
• kusuta;
• Kupsinjika maganizo: hyperlymphocytosis imapezeka mwa odwala omwe amakumana ndi zoopsa zosiyanasiyana, opaleshoni kapena mtima, kapena panthawi yolimbitsa thupi (pobereka);
• Opaleshoni kuchotsa ndulu.

Hyperlymphocytosis imatha kuyambitsidwa ndi:

• Khansa ya m'magazi, makamaka lymphoid leukemia;
• Lymphomas;
• Kutupa kosatha, makamaka m'mimba (matenda a Crohn).

matenda

Hyperlymphocytosis imapezeka pakuyezetsa magazi kosiyanasiyana:

• Kuwerengera kwathunthu kwa magazi: kuyesa kwachilengedwe komwe kumapangitsa kuti athe kuwerengera ma cell omwe amayenda m'magazi (maselo oyera, maselo ofiira amagazi ndi mapulateleti) ndikuzindikira kuchuluka kwa maselo oyera amagazi (makamaka ma lymphocyte);
• Kuwerengera kwa magazi kukuwonetsa kuchuluka kwa ma lymphocyte, dokotala amawunika magazi pansi pa maikulosikopu kuti adziwe momwe ma lymphocyte alili. A heterogeneity lalikulu mu morphology ya lymphocytes zambiri amakhala mononucleosis syndrome, ndi kukhalapo kwa mwana maselo ndi khalidwe la khansa ya m'magazi kapena lymphomas;
• Pomaliza, mayeso owonjezera a magazi amathanso kudziwa mtundu wa lymphocyte (T, B, NK) womwe umachulukitsidwa kuti uthandizire kudziwa chomwe chimayambitsa.

Anthu okhudzidwa

Hyperlymphocytosis imakhudza ana onse omwe nthawi zonse amakhala otakataka komanso osakhalitsa, komanso akuluakulu omwe amatha kukhala osakhalitsa kapena osatha (ndiwo omwe ali ndi chiyambi choyipa mu 50% ya milandu).

Payokha, kuchuluka kwa ma lymphocyte sikumayambitsa zizindikiro. Komabe, mwa anthu omwe ali ndi lymphoma ndi leukemias, hyperlymphocytosis ingayambitse:

• Malungo ;
• Thukuta usiku;
• Kuchepa thupi.

Chithandizo cha hyperlymphocytosis chimadalira zomwe zimayambitsa, kuphatikizapo:

• Symptomatic mankhwala ambiri tizilombo matenda kuchititsa pachimake hyperlymphocytosis;
• Mankhwala opha tizilombo toyambitsa matenda;
• Chemotherapy, kapena nthawi zina stem cell transplantation, kuchiza khansa ya m'magazi;
• Kuchotsa chifukwa (kupsinjika, kusuta)

Kupewa pachimake hyperlymphocytosis kumaphatikizapo kupewa matenda a virus ndi mabakiteriya omwe angayambitse vutoli:

• Katemera, makamaka motsutsana ndi mumps, rubella, chifuwa chachikulu kapena chifuwa chachikulu;
• Kugwiritsa ntchito kondomu nthawi zonse pogonana pofuna kuteteza ku HIV.

Komano, palibe njira yodzitetezera ya hyperlymphocytosis.