Lactic acid imapangidwa m'magulu osiyanasiyana a thupi pamene mpweya ulibe. Izi zimakhala choncho makamaka panthawi yochita masewera olimbitsa thupi. Mlingo wake ndikuyezetsa magazi kumayikidwa kuti azindikire lactic acidosis.

Lactic acid ndi chinthu chopangidwa ndi maselo ofiira a m'magazi, maselo a minofu, impso, maselo a khungu, komanso amtima, panthawi ya anaerobic kuwonongeka kwa shuga. Iyi ndi njira yamankhwala yomwe imachitika pamene mpweya ulibe ndipo sulola kuti glucose apangidwe kwathunthu. Izi ndi mwachitsanzo zomwe zimachitika panthawi ya infarction ya myocardial kapena kuchita masewera olimbitsa thupi kwambiri.

Zindikirani kuti pansi pazikhalidwe za aerobic, mwachitsanzo, pamaso pa okosijeni, zinthu zomaliza zogwiritsira ntchito shuga si lactic acid koma madzi ndi mpweya woipa.

Pochita nawo masewera olimbitsa thupi, thupi limafunikira mpweya wochulukirapo kuposa momwe lingatulukire ndi zomwe zimatchedwa aerobic process. Chifukwa chake amakhazikitsa njira za anaerobic kuti apange mphamvu. Ndipo lactic acid ndi chotulukapo cha zochita zamankhwala izi.

Ambiri a lactic acid opangidwa m'maselo a minofu amapita m'magazi ndipo amachotsedwa ku minofu ya minofu mkati mwa mphindi 30 mutasiya kuchita masewera olimbitsa thupi. Minofu ina, monga chiwindi, impso kapena mtima, imagwira lactic acid ndikuigwiritsa ntchito ngati gwero lamphamvu.

Dokotala amalembera kusanthula kwa lactic acid kuti awone momwe makutidwe ndi okosijeni amthupi azitha kuzindikira lactic acidosis. Ndiko kusokonezeka kwa acid-base balance ya thupi chifukwa cha kuchuluka kwa lactic acid.

Zizindikiro zina ndizomwe zimachitikira kuukiraku. Izi zikuphatikizapo:

• kuchepa kwa magazi (izi zimatchedwa hypovolemia);
• mkhalidwe wa mantha;
• kupuma mozama komanso kofulumira (izi zimatchedwa hyperventilation);
• ululu umene nthawi zambiri zimafalikira;
• kukokana kwa minofu;
• kapena ngakhale nseru ndi kusanza.

Makhalidwe abwino a lactic acid m'magazi a venous ali pakati pa 4,5 ndi 19,8 mg / dl.

Dziwani kuti zikhulupirirozi zitha kusintha pang'ono kutengera labotale yowunikira zamankhwala yomwe imayesa ndi njira zomwe amagwiritsa ntchito.

Zomwe zimapezedwa sizili m'gulu lazinthu izi, zikutanthauza kuti minofuyo siyikulandira mpweya wokwanira.

Kuchuluka kwa lactic acid kungakhale chizindikiro cha:

• matenda a chiwindi;
• kupuma, aimpso kapena ventricular kulephera;
• kumangidwa kwa mtima;
• matenda oopsa omwe amakhudza thupi lonse (sepsis);
• hypoxia, mwachitsanzo, kuchepa kwa mpweya m'magazi;
• mowa wakupha;
• a khansa ya m'magazi ;
• kapena shuga.

Kuwunika kumakhala ndi magazi a venous, omwe nthawi zambiri amakhala pamtunda wa chigongono.

Ndikoyenera kuti musachite zolimbitsa thupi musanachite kusanthula, komanso kukhala pamimba yopanda kanthu. Njira yabwino ndikutenga chitsanzo mutagona kwa mphindi 15.

Pankhani ya lactic acidosis, mwachitsanzo, kuchuluka kwa lactic acid m'thupi komwe kumachulukana mwachangu kuposa momwe kungathekere, mankhwalawa amakhala ndi mpweya wabwino komanso kulowetsedwa. ma bicarbonates.

Pankhani yochita masewera olimbitsa thupi, ndizotheka kuchepetsa kuchuluka kwa lactic acid mwa kuthira madzi moyenera (ndikoyenera kumwa madzi musanayambe, panthawi komanso pambuyo pa maphunziro).

Dziwani kuti kumwa mankhwala ena kumatha kukhala chifukwa cha metabolic acidosis. Chifukwa chake ndikofunikira kudziwitsa dokotala zamankhwala anu, kuti muwonetse zomwe mwakupatsani posachedwa.