Kafukufuku wathandizira kupita patsogolo kwakukulu mu chithandizo cha zizindikiro du lupus. Komabe, palibe mankhwala enieni a matendawa. Mankhwala amapangitsa moyo kukhala wabwino mwa kuchepetsa kuchulukira kwa zizindikiro, kuchepetsa chiopsezo cha zovuta komanso kukulitsa nthawi ya moyo.

Bwinobwino, mankhwala a lupus ndi mankhwala ochepa momwe ndingathere komanso kwa nthawi yochepa kwambiri, kuti muchepetse chipwirikiticho. Anthu ena safuna mankhwala aliwonse, ena amangogwiritsa ntchito ngati akufunikira kapena kwanthawi yochepa (zowopsa), koma anthu ambiri amafunika kumwa mankhwala kwa nthawi yayitali.

Mankhwala osokoneza bongo

Mankhwala opweteka (mankhwala osagwiritsidwa ntchito poletsa kutupa). Acetaminophen (Tylenol®, Atosol®) ndi mankhwala oletsa kutupa²⁵ pa-the-counter (ibuprofen, Advil®, kapena Motrin) angagwiritsidwe ntchito kuthetsa ululu zimfundo, pamene lupus silili lolimba kwambiri kapena kuphulika kwake sikuli kwakukulu kwambiri. Komabe, madokotala samalimbikitsa kuti anthu omwe ali ndi a kwambiri lupus kutenga mankhwala ochepetsa ululu paokha. Mankhwalawa amatha kuonjezera chiopsezo cha zovuta za lupus, makamaka kuwonongeka kwa impso. Zingatenge nthawi kuti mupeze mankhwala oyenera oletsa kutupa ndikusintha mlingo ndi dokotala wanu.

Mankhwala a Corticosteroids. Corticosteroids, makamaka prednisone ndi methylprednisone, ndi mankhwala othandiza kwambiri oletsa kutupa. lupus, pamene matendawa amakhudza ziwalo zingapo. Kugwiritsidwa ntchito kuyambira koyambirira kwa 1960s motsutsana ndi lupus, prednisone (Deltasone®, Orasone®) mwachangu idakhala mankhwala ofunikira pakuwongolera moyo wa odwala. Zimathandizira kuchepetsa kutupa ndikuwongolera zizindikiro, makamaka ndi zoyaka. Komabe, corticosteroids yotengedwa mu Mlingo waukulu kapena kwa nthawi yayitali ingayambitse mndandanda waZotsatira zoyipa, kuphatikizapo kuyamba kwa mikwingwirima, kusinthasintha kwa maganizo, matenda a shuga^25-26 , mavuto a masomphenya (cataracts), kuwonjezeka kwa magazi ndi mafupa ofooka (osteoporosis). Mlingo umasinthidwa bwino ndi dokotala kuti mupeze zotsatira zochepa momwe zingathere. Pakanthawi kochepa, zotsatira zazikulu za corticosteroids ndizolemera komanso kutupa kwa nkhope ndi thupi (edema). Kugwiritsa ntchito calcium ndi vitamini D kumathandizira kuchepetsa chiopsezo cha osteoporosis.

Ma creams ndi mankhwala am'deralo. Nthawi zina zotupa zimathandizidwa ndi zonona, nthawi zambiri ndi corticosteroids.

Mankhwala oletsa malungo. Hydroxychloroquine (Plaquenil®) ndi chloroquine (Aralen®) - mankhwala omwe amagwiritsidwanso ntchito pochiza malungo - ndi othandiza pochiza lupus pamene nonsteroidal odana ndi kutupa mankhwala sikokwanira. Amachepetsa ululu ndi kutupa m'malo olumikizirana mafupa komanso amathandizira kuchiza totupa. Mankhwala aliwonsewa amatha kutengedwa kuyambira masika mpaka kugwa kuti apewe kuyambika kwa zotupa pakhungu. dzuwa. Hydroxychloroquine imagwiritsidwanso ntchito ngati chithandizo choyambirira kuti mupewe kuyambiranso. Zotsatira zazikulu za mankhwalawa ndi kupweteka kwa m'mimba ndi nseru.

Odwala matenda opatsirana pogonana. Ma immunosuppressive agents amachepetsa ntchito ya chitetezo chamthupi motsutsana ndi ziwalo zake ndi minofu yake. Mankhwala amphamvuwa amagwiritsidwa ntchito mwa anthu ochepa pamene prednisone sichithandiza ndi zizindikiro kapena pamene imayambitsa mavuto ambiri. Iwo amafunikira pamene lupus zimakhudza ntchito ya chiuno kapena ndondomeko mantha. Zomwe zimagwiritsidwa ntchito kwambiri ndi cyclophosphamide (Cytoxan®), azathioprine (Imuran®) ndi mycophenolate mofetil (Cellcept®). Odwala ena, methotrexate (Folex®, Rheumatrex®) ingagwiritsidwenso ntchito pa mlingo wochepa ngati chithandizo chothandizira. Mankhwalawa amakhalanso ndi zotsatira zake, zofunika kwambiri zomwe zimakhala ndi chiopsezo chachikulu cha matenda komanso chiopsezo chachikulu chokhala ndi khansa. Mankhwala atsopano, belimumab (Benlysta) angakhale othandiza pa matenda a lupus; zotsatira zake zotheka ndi nseru, kutsegula m'mimba ndi kutentha thupi²⁵.

Zina

Kulowetsedwa kwa Immunoglobulin. Kukonzekera kwa Immunoglobulin (antibody) kumachokera ku magazi a opereka. Akalowetsedwa m'mitsempha, amakhala ndi anti-kutupa chifukwa amalepheretsa pang'ono ma antibodies, mwachitsanzo, ma antibodies omwe amatsutsana ndi thupi ndipo amatenga nawo gawo mu lupus. Kulowetsedwa kwa Immunoglobulin kumasungidwa kwa milandu ya lupus kugonjetsedwa ndi mankhwala ena, monga corticosteroids.