Amatchedwanso "mankhwala abodza", ma placebo amakhala ndi zotsatira zake kuchiza popanda, komabe, okhala ndi mfundo yogwira ntchito yolola machiritso. Madzi a shuga, kapisozi wa ufa, ndi zina zambiri, mawonekedwe awo ndi mafotokozedwe ake ndi osiyanasiyana koma onse amakhala ndi matsenga ofanana: amathandizira muubongo kupanga ma endorphin, mahomoni osangalatsa ndi mpumulo. 

Kumwa mankhwala opha ululu ndikumva bwino pamene umezedwa, podziwa kuti zimatenga pafupifupi ola ½ kuti thupi lilowerere ndikupangitsa kuti likhale logwira ntchito, ndizomwe zimatchedwa placebo effect. .