Matenda a amalinyero omwe amangodya zamzitini powoloka panyanja, matenda a Beriberi amalumikizidwa ndi kusowa kwa vitamini B1. Chofunika kwambiri kwa thupi, kuperewera kumeneku ndi komwe kunayambitsa matenda a ubongo ndi amtima, nthawi zina osasinthika. Kuphatikizika kwake koyambirira kudzera m'zakudya ndi chithandizo kumalola kuthandizidwa. 

Matenda akusowa kudziwika kuyambira ku East kuyambira zaka za m'ma chakhumi ndi chisanu ndi chiwiri ku Asia maphunziro amene ankadya mpunga woyera okha, izo zinawonedwanso amalinyero amene amadya chakudya zamzitini okha paulendo wawo wautali panyanja pamaso kumvetsa kuti kupewa anadutsa zakudya zambiri mavitamini, makamaka vitamini B1. Chifukwa chake dzina lakuti Beriberi la vitamini B. 

Thupi la munthu silingathe kupanga vitamini imeneyi ndipo limafunikira chakudya chokwanira kuti kagayidwe kake kagwire ntchito moyenera komanso moyenera.

Vitaminiyi imapezekanso muzakudya zambiri zanthawi zonse monga tirigu, nyama, mtedza, nyemba kapena mbatata.

Kuperewera kwake kukudetsabe nkhawa masiku ano makamaka mayiko omwe akutukuka kumene omwe akudwala matenda osowa zakudya m'thupi ndipo amakonda kudya zakudya zokhala ndi ma carbohydrate oyeretsedwa (mpunga woyera, shuga woyera, starches woyera ...). 

Koma zimathanso kuchitika m'zakudya zosayenera monga zakudya zamasamba, kapena ngati matenda a anorexia nervosa achichepere. Matenda ena amathanso kukhala chifukwa cha kuchepa kwa vitamini B1 monga hyperthyroidism, kuyamwa kwamatumbo kwanthawi yayitali monga kutsekula m'mimba kapena kulephera kwa chiwindi. Amapezeka mwa odwala omwe ali ndi vuto lakumwa mowa mwauchidakwa komanso matenda enaake a chiwindi.

Kuperewera kwa vitamini B1 kumabweretsa kuwonongeka kwa minyewa yotumphukira (neuropathy), ya zigawo zina zaubongo (thalamus, cerebellum, etc.) ndipo kumachepetsa kufalikira kwaubongo pakuwonjezeka kwa kukana kwa mitsempha yaubongo kukuyenda kwa magazi. Zimakhudzanso mtima, womwe umatambasuka komanso sugwira bwino ntchito yake ya mpope kuti magazi aziyenda m'thupi (kulephera kwa mtima). 

Potsirizira pake, kusowa kumeneku kungayambitse kufalikira kwa ziwiya (vasodilation) zomwe zimayambitsa edema (kutupa) kwa mapazi ndi miyendo.

Pamene kuperewera kuli kochepa, zizindikiro zochepa chabe zomwe sizidziwika bwino zimatha kuchitika monga kutopa (kuchepa kwa asthenia), kukwiya, kukumbukira kukumbukira ndi kugona.

Koma zikadziwika kwambiri, zizindikiro zingapo zimapezeka mwamagome awiri:

Mu mawonekedwe youma ndi 

• symmetrical zotumphukira neuropathies (polyneuritis) mbali zonse za m'munsi miyendo, ndi kumva kumva kulasalasa, moto, cramping, kupweteka kwa miyendo;
• kuchepetsa kukhudzika kwa miyendo yapansi (hypoaesthesia) makamaka kugwedezeka, kumva dzanzi;
• kuchepa kwa minofu (atrophy) ndi mphamvu ya minofu yomwe imayambitsa kuvutika kuyenda;
• kuchepetsa kapena kuthetsedwa kwa tendon reflexes (Achilles tendon, patellar tendon, etc.);
• zovuta kukwera kuchoka pamalo ogwada kupita ku malo oima;
• zizindikiro za ubongo ndi ziwalo za maso (Wernicke's syndrome), kuyenda movutikira, kusokonezeka maganizo, kuvutika kuchitapo kanthu (abulia), amnesia ndi kuzindikira zabodza (matenda a Korsakoff).

Mu mawonekedwe yonyowa

• kuwonongeka kwa mtima ndi kulephera kwa mtima, kuwonjezeka kwa mtima (tachycardia), kukula kwa mtima (cardiomegaly);
• kuwonjezeka kwamphamvu kwa mitsempha ya jugular (pakhosi);
• kupuma movutikira (dyspnea);
• edema ya m'munsi miyendo (mapazi, bondo, ng'ombe).

Palinso zizindikiro za m'mimba mu zovuta izi ndi ululu m'mimba, nseru, kusanza. 

Potsirizira pake, mwa makanda, mwanayo amawonda, amamveka mawu kapena alibe mawu (sakufuulanso kapena kubuula pang'ono), amadwala matenda otsegula m'mimba ndi kusanza ndipo amavutika kupuma.

Mayeso owonjezera amachitidwa ngati akukayikira Beriberi kuti atsimikizire kuti ali ndi matendawa ndikuyesa kuperewera (thiamine mono ndi diphosphate). Kujambula kwa Magnetic Resonance Imaging (MRI) muubongo kumathanso kuperekedwa kuti muwone zolakwika zomwe zimalumikizidwa ndi kusowa kwa Vit B1 (zotupa zapawiri za thalamus, cerebellum, cerebral cortex, etc.).

Chithandizo cha matenda a Beriberi ndikuwonjezera vitamini B1 mwachangu momwe mungathere kuti mupewe zotsatira zosasinthika. Mankhwala a prophylaxis amathanso kukhazikitsidwa mwa anthu omwe ali pachiwopsezo (odwala matenda oledzeretsa komanso matenda enaake, odwala matenda osowa zakudya m'thupi omwe akudwala AIDS, kusowa kwa zakudya m'thupi, ndi zina).

Pomaliza, kupewa tsiku ndi tsiku kumaphatikizapo kulemeretsa zakudya zosiyanasiyana ndi nyemba (nandolo, nyemba, nandolo, etc.), mbewu zonse (mpunga, mkate ndi tirigu wonse, ndi zina zotero), yisiti wolemera mu Vit B1 ndi mbewu (walnuts, hazelnuts, glitches). …). Muyenera kupewa mpunga woyera ndi chirichonse chomwe chimayeretsedwa kwambiri ngati shuga woyera ndikuonetsetsa kukonzekera kukhitchini komwe sikuwononga mavitamini ambiri.