Mosiyana ndi mankhwala wamba omwe amafuna kudzipatula mamolekyu, zomera zimayimira zinthu zomwe zimagwira ntchito mu synergy, ndipo ndizowonjezera izi za zinthu zomwe zili pa chiyambi cha katundu wawo wambiri. Atitchoku (cynara scolymus) ndiye chitsanzo chodziwika bwino kwambiri chokhudzana ndi ma molecule 4 (asidi citric, malic, succinic et cynaropicrine) zomwe, zomwe zimatengedwa kudzipatula, sizigwira ntchito kwambiri, koma synergy yawo imakhala ndi mphamvu ya pharmacological pa chiwindi ndi ntchito ya biliary.

Titha kupita mpaka kunena kuti zomera zimapangidwira kuti zitichiritse popeza mamolekyu ena a zomera amakhala ndi chiyanjano chachilengedwe ndi zolandilira m'maselo athu. Mwachitsanzo, morphine kuchokera ku poppy (papaver somniferum) amamangiriza ku otchedwa morphine receptors a chapakati mantha dongosolo. Zomwe zimagwiritsidwa ntchito ndi valerian (valerian officinalis) ndi passionflower (passionflower wokhazikika) kuphatikiza ndi zolandilira muubongo za benzodiazepines, mamolekyulu oziziritsa. M'lingaliro limeneli, zomera zikagwiritsidwa ntchito bwino ndi kuzolowera zosowa zathu, zimayimira mankhwala enieni.