OCD iyenera kukhala chifukwa cha a kusowa kwa serotonin mu ubongo. Mankhwala omwe amagwiritsidwa ntchito makamaka amachulukitsa kuchuluka kwa serotonin mu ma synapses (mphambano pakati pa ma neuron awiri) poletsa kubwezeretsanso komweku. Mankhwalawa amatchedwa serotonin reuptake inhibitors. Amathandizira kupititsa uthenga wamanjenje.

Njira zazikuluzikulu zosankhira serotonin reuptake inhibitor (SSRI) zomwe zimaperekedwa ndi:

• Fluvoxamine (Floxyfral® / Luvox®)
• Fluoxetine (Prozac®)
• Sertraline (Zoloft ®)
• Paroxetine (Deroxat® / Paxil®)
• Escitalopram (Seroplex® / Lexapro®)
• Citalopram (Seropram® / Celexa®)

Amagwira ntchito pa OCD patatha milungu ingapo akuchiritsidwa. Chithandizo nthawi zambiri chimakhala zaka zingapo. Ngati matendawa atulukanso, mlingowo ukhoza kukulitsidwa kapena kuyesedwa ndi molekyulu yatsopano. Oposa theka la odwala amawona kuti thanzi lawo likuyenda bwino chifukwa cha mankhwala osokoneza bongo.

Clomipramine (Anafranil®), yomwe ili m'gulu lina la opanikizika, ma tricyclic antidepressants, omwe adawonetsedwa koyamba kuti ndi othandiza mu OCD, amathanso kulembedwa.¹⁶. Nthawi zambiri amagwiritsidwa ntchito ngati mzere wachiwiri, ngati mankhwala oyambawo sanawonetsedwe kuti ndi othandiza, popeza zoyambitsa zake zimakhala zofunikira.

Mlingo woperekedwa kwa OCD nthawi zambiri umakhala wapamwamba kuposa chithandizo cha kukhumudwa. Ngati chithandizocho chikutsimikizira kuti sichikugwira ntchito, a psychiatrist amafunsidwa chifukwa ma molekyulu ena monga lithiamu kapena buspirone (Buspar®) amatha kuyesedwa.

Anxiolytics omwe ali mgulu la benzodiazepine atha kulembedwa kuti athetse nkhawa. Mwachitsanzo, clonazepam (Rivotril®) yawonetsa zina zothandiza pochiza OCD. Komabe, kuwopsa kwa kusinthasintha kwa malingaliro, kukwiya komanso malingaliro ofuna kudzipha kwatchulidwapo.¹⁷.

Kukondoweza kwamagetsi, komwe kumagwiritsidwa ntchito mu matenda a Parkinson, kwakhala ndi zotsatira zina mu OCD yovuta kapena yosagwiritsa ntchito mankhwala¹⁸. Kukondoweza kwakuzama kwa ubongo (DBS) kumaphatikizapo kuyika ma elekitirodi muubongo ndikuwalumikiza ku chosakanizira chomwe chimapereka mphamvu yamagetsi. Njira yowonongekayi ikuyesabe¹⁹. Kutsitsimutsa kocheperako, kosunthira maginito (kutumiza maginito osapweteka kudzera pa coil) kungaperekedwe.

Zovuta zomwe zimakhudzana ndi OCD zimayeneranso kuyendetsedwa.

Chithandizo cha matenda osokoneza bongo nthawi zambiri chimaphatikizapo chithandizo chamakhalidwe ndi kuzindikira. Mankhwalawa cholinga chake ndikuchepetsa nkhawa zomwe zimakhudzana ndi kukhumbira komanso kuchepetsa kukakamizidwa komwe kumachitika chifukwa chakukonda izi. Magawowa atha kukhala ndi zochitika zolimbitsa thupi, munthu yemwe akukumana ndi zomwe akuopa, kupumula kapena sewero.

Mankhwala osokoneza bongo ndi ma psychotherapies atha kuphatikizidwa ndipo awonetsedwa kuti ndi othandiza. M'malo mwake, magawo awiri mwa atatu mwa odwala omwe amathandizidwa amatha kuwona kuti kuchepa kwawo kumachepa. Kuphatikiza kwa ziwirizi kumaperekedwa mwachindunji pakakhala zovuta zazikulu kapena mankhwala atalephera.

Nthawi zina matendawa amalimbana ndi mankhwala. Izi nthawi zambiri zimagwira ntchito kwa anthu omwe ali ndi vuto lalikulu omwe amakhalanso ndi vuto la kupuma komanso kusadya. Kugonekedwa kuchipatala kungakhale kofunikira.