Zamkatimu
Kuyeza kwa cystic fibrosis wakhanda
Tanthauzo la kuyezetsa wakhanda kwa cystic fibrosis
La cystic fibrosis, Amatchedwanso cystic fibrosis, ndi matenda obadwa nawo omwe amawonekera makamaka ndi kupuma ndi m'mimba zizindikiro.
Ndilo matenda amtundu wanthawi zonse pakati pa anthu ochokera ku Caucasus (omwe amapezeka pafupifupi 1/2500).
Cystic fibrosis imayamba chifukwa cha kusintha kwa jini, the Mtengo wa CFTR, zomwe zimayambitsa kusagwira ntchito kwa mapuloteni a CFTR, omwe amawongolera kusinthana kwa ayoni (chloride ndi sodium) pakati pa maselo, makamaka pamlingo wa bronchi, kapamba, matumbo, machubu a seminiferous ndi thukuta. . Nthawi zambiri, zizindikiro zowopsa kwambiri ndi kupuma (matenda, kupuma movutikira, kuchulukitsidwa kwa ntchentche, etc.), kapamba ndi m'mimba. Tsoka ilo, pakadali pano palibe chithandizo chochizira, koma chithandizo chamankhwala msanga chimapangitsa moyo wabwino (kupuma ndi zakudya zopatsa thanzi) ndikusunga chiwalo momwe kungathekere.
Chifukwa chiyani kuyezetsa khanda kwa cystic fibrosis?
Matendawa ndi owopsa kuyambira ali mwana ndipo amafunika kuwongolera msanga. Ndicho chifukwa chake ku France, ana onse obadwa kumene amapindula popimidwa cystic fibrosis, pakati pa zina. Ku Canada, mayesowa amangoperekedwa ku Ontario ndi Alberta. Quebec sinakhazikitse kuwunika mwadongosolo.
Ndi zotsatira zotani zomwe tingayembekezere kuchokera pakuyezetsa khanda kwa cystic fibrosis?
Kuyesaku kumachitika ngati gawo lowunikira matenda osiyanasiyana osowa pa 72st Ola la moyo wa ana obadwa kumene, kuchokera ku magazi omwe atengedwa pobaya chidendene (Guthrie test). Palibe kukonzekera kofunikira.
Dontho la magazi limayikidwa pa pepala lapadera la fyuluta, ndikuwumitsa musanatumize ku labotale yowunikira. Mu labotale, kuyesa kwa immunoreactive trypsin (TIR) kumachitika. Molekyuyi imapangidwa kuchokera ku trypsinogen, yomwe imapangidwa ndi kapamba. Kamodzi m’matumbo aang’ono, trypsinogen imasinthidwa kukhala trypsin yogwira ntchito, puloteni yomwe imagwira ntchito m’kugaya kwa mapuloteni.
M'makanda ndi cystic fibrosis, trypsinogen imavuta kulowa m'matumbo chifukwa imatsekeka m'chiwindi chifukwa cha kukhalapo kwa mamina okhuthala modabwitsa. Zotsatira zake: imadutsa m'magazi, pomwe imasandulika kukhala "immunoreactive" trypsin, yomwe imakhala yochulukirapo modabwitsa.
Ndi molekyulu iyi yomwe imadziwika panthawi ya mayeso a Guthrie.
Ndi zotsatira zotani zomwe tingayembekezere kuchokera pakuyezetsa khanda kwa cystic fibrosis?
Ngati mayeso akusonyeza kukhalapo kwa abnormal kuchuluka kwa immunoreactive trypsin m’mwazi, makolowo adzafunsidwa kuti mwana wakhandayo ayesedwenso kuti atsimikizire kuti ali ndi matenda a cystic fibrosis. Ndiye funso lozindikira masinthidwe (ma) a jini Mtengo wa CFTR.
Mayeso otchedwa "thukuta" amathanso kuchitidwa kuti azindikire kuchuluka kwa klorini mu thukuta, khalidwe la matendawa.
Werengani komanso: Zonse zomwe muyenera kudziwa zokhudza cystic fibrosis (cystic fibrosis) |