Candida albicans ndi bowa lomwe nthawi zambiri limapezeka muzomera za mucous nembanemba. Sizoyambitsa matenda ndipo zimathandizira kuti ma microbiota athu azikhala bwino. Komabe, kuchulukirachulukira kwa yisiti ndi matenda: amatchedwa candidiasis.

Candida albicans ndi bowa wonga yisiti wamtundu wa Candida komanso wa banja la saccharomycetaceae. Ma Candida albicans amagawidwa m'gulu la bowa wa asexual omwe kubereka kwawo kumakhala kofanana kwambiri. Candida albicans ndi chamoyo cha diploid chomwe chili ndi ma chromosomes 8. Heterozygosity yake imapatsa mphamvu yosinthira kumadera osiyanasiyana.

Candida albicans mwachibadwa amapanga zomera za mucous nembanemba wa munthu. Kukhalapo kwake si pathological. Tizilombo toyambitsa matenda timapeza m'mimba ya 70% ya anthu akuluakulu athanzi. Komabe, kusalinganika kwa mahomoni kapena chitetezo chamthupi kumatha kuyambitsa kuchulukitsidwa kwapang'onopang'ono kwa bowa komwe kumayambitsa zizindikiro zina. Tikukamba za candidiasis kapena mycosis.

C. albicans virulence factor imapangitsa kuti izi zichuluke:

• dimorphism (kusintha kwa yisiti kukhala bowa malingana ndi malo ozungulira);
• zomatira (chiwerengero chachikulu cha zolandilira pamwamba zomwe zimalola ma C. albicans kumamatira mosavuta ku maselo a wolandirayo);
• zotupa za enzymatic;
• etc.

Matenda a C. albicans amatha kupezeka kumaliseche, mkamwa kapena m'mimba. Kuphatikiza apo, kuchuluka kwa ma Candida albicans pakhungu sikwachilendo ndipo kumayambitsa zizindikiro zapakhungu. Nthawi zambiri, odwala omwe ali ndi chitetezo chamthupi, C. albicans amatha kukhala ndi chiwalo chimodzi kapena zingapo kapena thupi lonse: timalankhula za systemic candidiasis. Pankhaniyi, chiopsezo cha imfa ndi pafupifupi 40%.

Candida albicans ndi tizilombo tating'onoting'ono tating'onoting'ono ta anthu ndi nyama zamagazi ofunda. Iwo alipo m`kamwa, m`mimba ndi maliseche mucous nembanemba, mu mawonekedwe a blastospores, amaona kuti saprophytic mawonekedwe amene amakhala symbiosis ndi khamu zamoyo. M'maphunziro athanzi, yisiti imagawidwa mosiyanasiyana kutengera malo opangira zitsanzo, chosungira chachikulu chimakhalabe m'mimba:

• khungu (3%);
• nyini (13%);
• thirakiti ano-rectal (15%);
• pakamwa pakamwa (18%);
• m'mimba ndi duodenum (36%);
• jejunum ndi ileamu (41%).

Komabe, ziwerengerozi ziyenera kuwonedwa mosamala popeza njira zotsatsira sizifanana nthawi zonse ndipo malo opangira sampuli samakhala ndi malo ofanana.

Choncho ma C.albicans ndi ofunika kuti tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda. Komabe, pamene izi mu mawonekedwe ake commensal ndi chitetezo chitetezo chathyoka, symbiosis izi zimakhala parasitic. Izi zimabweretsa matenda opatsirana otchedwa candidiasis.

Candidiasis ndi matenda omwe amayamba chifukwa cha bowa Candida albicans. Si matenda opatsirana: yisiti ilipo kale mu thupi, mu mucous nembanemba, pakamwa, m'mimba dongosolo ndi kumaliseche. Candidiasis imalumikizidwa ndi kuchulukirachulukira kwa ma Candida albicans, komweko komwe kumachitika chifukwa cha kusalinganika kwa chitetezo chamthupi kapena mahomoni kapena kufowoka kwa tizilombo tating'onoting'ono. Kuonjezera apo, matenda a yisiti maliseche samatengedwa ngati matenda opatsirana pogonana (STIs), ngakhale kuti kugonana ndi chiopsezo cha matenda a yisiti (zotsirizirazi zimabweretsa kufooka kwa zomera zoberekera).

Komabe, kufala kwa ma C. albicans kumatheka kudzera mu ndowe, kutuluka m'malovu kapena kudzera m'manja. Mzipatala, C. albicans amaimira chifukwa chachikulu cha Matenda osokoneza bongo mwayi.

Zowopsa

Zina mwazowopsa zikuwonetsa kukula kwa candidiasis:

• mobwerezabwereza maphunziro a maantibayotiki;
• mankhwala omwe amalepheretsa chitetezo cha mthupi (corticosteroids, immunosuppressants, chemotherapy, etc.);
• a immunodepression (wobadwa nawo, wolumikizidwa ndi kachilombo ka HIV kapena kumuika).

Matenda a yisiti kumaliseche ndi candidiasis kawirikawiri, zomwe zimakhudza 10 mpaka 20% ya amayi panthawi yogonana. Amayamikiridwa ndi:

• kusintha kwa mahomoni;
• kutenga estrogen-progestogen kulera;
• thukuta ;
• mathalauza othina kwambiri;
• zovala zamkati zosapangidwa ndi thonje (makamaka zingwe);
• kuvala zovala za panty;
• ukhondo;
• kugonana kwanthawi yayitali.