Hyperleukocytosis imatanthauzidwa ngati kuwonjezeka kwa maselo oyera a magazi pamwamba pa maselo 10 pa microliter ya magazi, m'mayesero awiri otsatizana. Zomwe zimachitika kawirikawiri, kusiyana kuyenera kupangidwa pakati pa benign hyperleukocytosis ndi malignant hyperleukocytosis. Chotsatiracho chikhoza kukhala chizindikiro cha matenda a bakiteriya monga angina, a tizilombo toyambitsa matenda monga mononucleosis komanso kawirikawiri za matenda aakulu monga khansa ya m'magazi. Zizindikiro ndi kasamalidwe ka hyperleukocytosis zimadalira nkhani ndi chifukwa chake.

Ma leukocyte, omwe amatchedwanso maselo oyera a magazi, amagwira ntchito yofunika kwambiri poteteza thupi lathu ku tizilombo toyambitsa matenda ndi zinthu zakunja. Kuti zikhale zogwira mtima, chiwerengero chokwanira cha maselo oyera a magazi chiyenera kudziwitsidwa za kukhalapo kwa tizilombo toyambitsa matenda kapena zinthu zachilendo. Kenako amapita kumene ali, kukawononga ndi kuwagaya.

• neutrophils;
• ma lymphocytes;
• ma monocytes;
• eosinophils;
• basophils.

Nthawi zambiri, munthu amapanga maselo oyera amagazi pafupifupi 100 biliyoni patsiku. Izi zimawerengedwa ngati chiwerengero cha maselo oyera a magazi pa microliter imodzi ya magazi. Chiwerengero chokhazikika chili pakati pa 4 ndi 000 ma cell pa microliter.

Hyperleukocytosis ndi kuwonjezeka kwa chiwerengero cha maselo oyera a magazi m'magazi, pamwamba pa maselo 10 pa microliter imodzi ya magazi. Hyperleukocytosis imafotokozedwa kuti ndi yocheperako pakati pa 000 ndi 10 maselo oyera amagazi pa microliter imodzi ya magazi ndi frank pamwamba pa 000 maselo oyera a magazi pa microlita imodzi ya magazi.

• polynucleosis pankhani kuchuluka kwa neutrophils, eosinophils kapena basophils;
• lymphocytosis pamene ndi kuwonjezeka kwa chiwerengero cha lymphocytes;
• monocytosis pankhani kuwonjezeka kwa chiwerengero cha monocytes.

Pakhoza kukhalanso hyperleukocytosis chifukwa cha maonekedwe a maselo omwe sali m'magazi:

• maselo a medullary, ndiko kuti, maselo opangidwa ndi m'mafupa ndi omwe, mu magawo osakhwima, amapita m'magazi;
• maselo oopsa kapena leucoblasts amene ndi zizindikiro za pachimake khansa ya m'magazi.

Hyperleukocytose

Hyperleukocytosis ikhoza kunenedwa kuti ndi yathupi, ndiye kuti yachibadwa:

• kutsatira zolimbitsa thupi;
• pambuyo pa kupsinjika kwakukulu;
• pa mimba;
• mu post-delivery.

Koma, nthawi zambiri, hyperleukocytosis ndi chitetezo chokwanira cha thupi ku:

• matenda a bakiteriya monga bakiteriya streptococcal angina;
• ma virus (mononucleosis, cytomegalovirus, hepatitis, etc.);
• matenda a parasitic;
• ziwengo (asthma, mankhwala ziwengo);
• mankhwala ena monga corticosteroids.

Nthawi zambiri, hyperleukocytosis ikhoza kukhala chizindikiro cha khansa ya m'mafupa, zomwe zimapangitsa kuti maselo oyera a magazi atuluke kapena achilendo kuchokera m'mafupa kupita m'magazi, monga:

• matenda a lymphocytic leukemia (CLL);
• matenda a myelogenous leukemia (CML);
• khansa ya m'magazi.

Polynucleose

Ponena za neutrophilic polynucleosis, imawoneka m'magawo ena amthupi monga:

• kubadwa;
• mimba;
• nthawi;
• masewera olimbitsa thupi;

ndipo makamaka pazochitika za pathological monga:

• tizilombo toyambitsa matenda (abscess kapena sepsis);
• matenda otupa;
• matenda a necrosis;
• khansa kapena sarcoma;
• kusuta.

Eosinophilic polynucleosis, kumbali ina, ili ndi zifukwa ziwiri zazikulu: ziwengo ndi majeremusi. Itha kulumikizidwanso ndi periarteritis nodosa, matenda a Hodgkin kapena khansa.

Basophilic polynucleosis ndiyosowa kwambiri ndipo imapezeka mu myeloid leukemia yosatha.

Lymphocytose

Hyperlymphocytosis imadziwika:

• ana pa matenda tizilombo kapena bakiteriya matenda monga chiphuphuphuphu;
• mwa akuluakulu kapena okalamba omwe ali ndi matenda a lymphocytic leukemia ndi matenda a Waldenström.

Monocytose

Monocytosis nthawi zambiri imasonyeza matenda opatsirana:

• matenda mononucleosis ;
• toxoplasmosis;
• cytomegalovirus matenda;
• kachilombo ka hepatitis;
• brucellosis;
• Matenda a Osler;
• chindoko chachiwiri.

Zizindikiro za hyperleukocytosis zidzakhala za matenda omwe amayamba. Mwachitsanzo, ndi matenda a virus, monga mononucleosis, zizindikiro zimaphatikizapo:

• malungo ;
• ma lymph nodes mu khosi;
• kutopa kwakukulu.

Kasamalidwe zimadalira nkhani ndi chifukwa cha hyperleukocytosis. Choncho zimasiyanasiyana malinga ndi chifukwa cha angina, chibayo kapena matenda a lymphoid leukemia.

• symptomatic mankhwala kwa tizilombo matenda;
• mankhwala opha tizilombo toyambitsa matenda;
• mankhwala antihistamine ngati chifuwa;
• mankhwala amphamvu a chemotherapy, kapena nthawi zina kuikidwa kwa stem cell, ngati pali khansa ya m'magazi;
• kuchotsedwa kwa zomwe zimayambitsa kupsinjika maganizo kapena kusuta.