Gawo lomaliza la msambo, gawo luteal limagwira gawo lalikulu pakubala kwazimayi polola, kukachitika ubwamuna, kukhazikika kwa dzira ndikusamalira mimba. Zikuyenda bwanji? Kodi iyenera kuthandizidwa liti? Zinthu zina zofotokozera.

Kusamba kumagawika magawo angapo, kofunikira pakupanga oocyte ndikusamalira mimba pambuyo pa umuna:

• gawo lotsatira Imatha pafupifupi masiku 14 kuyambira tsiku loyamba lakumapeto kwanu. Mchigawo chino, ma oocyte angapo okutidwa ndi thumba lawo lamchiberekero, khungu lomwe limafanana ndi thumba laling'ono, limayamba kukhwimitsa mothandizidwa ndi pituitary hormone (FSH). M'modzi yekha ndi amene adzathamangitsidwe.
• kusuntha: Pakati pa maola 24 mpaka 48, omwe amakhala pakati pa nthawi yamchiberekero, kutulutsa kwa luteinizing hormone (LH) kumawonjezeka kwambiri. Udindo wake: kupangitsa kuti follicle iphulike komanso kuthamangitsidwa kwa oocyte wokhwima. Izi zimatchedwa ovular kuyala kapena ovulation. Mumaola otengera ovulation, oocyte imapita kukazizira komwe imadikirira isanalandiridwe umuna… kapena kuthyoka.
• gawo luteal amapanga gawo lomaliza la kuzungulira kwa mazira. Nthawi imeneyi pakati pa ovulation ndi nthawi yotsatira imakhala pakati pa masiku 12 ndi 14. Pakati pa luteal komanso chifukwa chokhala ndi mahomoni, mimba yamchiberekero imasandulika kukhala gland yomwe imachokera ku mtundu wake wachikopa. Luteum yamtunduwu ndichinthu chofunikira kwambiri pakuyembekezera kukhala ndi pakati mtsogolo. Zowonadi, potulutsa estrogen ndi progesterone, imakonzekeretsa kulumikizana kwa chiberekero (endometrium) kuti ilandire dzira pakagwa umuna. Ndi chifukwa chake imakhuthala kwambiri pagawo lachiwirili mpaka tsiku la 20.

Pambuyo pa ovulation ndipo chifukwa cha gawo luteal, zochitika ziwiri ndizotheka:

Oocyte ndi umuna.

 Poterepa, kamwana kameneka kamakhazikika mu endometrium pafupifupi masiku 8 kuchokera umuna. Kukhazikika. Mahomoni angapo amatenga gawo lofunikira:

• mahomoni HCG, kapena chorionic gonadotropin, amabisika kotero kuti corpus luteum ipitilizabe kugwira ntchito kwa miyezi itatu. Ndi hormone iyi yomwe "imayesedwa" poyesa kutenga mimba ndipo imakupatsani mwayi wodziwa ngati mwakhala ndi pakati.
• estrogen ndi progesterone amabisidwa ndi corpus luteum kuti akhalebe ndi pakati. Kupanga kwa mahomoni kumeneku kumatha milungu ingapo mpaka malasalawo atakhala okonzeka kuonetsetsa kuti kusinthana kwamagesi ndi michere pakati pa mayi ndi mwana.

The oocyte si umuna.

 Ngati sipanakhalepo umuna, oocyte sikhala mu endometrium ndipo corpus luteum sakupanganso progesterone. Ndikutaya kwa mahomoni, zotengera zazing'ono za endometrium zimamana ndipo nembanemba zimatuluka zimayambitsa kukha magazi. Awa ndi malamulo. Gawo lotsatira limayambiranso.

Chizindikiro chodziwika bwino kwambiri cha gawo luteal ndikuwonjezeka kwa kutentha kwa thupi. Izi ndichifukwa choti progesterone yopangidwa ndi corpus luteum imapangitsa kuti thupi lizitha kutentha pafupifupi 0,5 ° C. Pambuyo pochepetsa kutentha panthawi yovundikira (mphindi "yotentha kwambiri" yozungulira), kutentha kwa thupi kumatsalira mozungulira 37,5 ° C (pafupifupi) mgawo lomalizirali. kusamba.

Chikhalidwe china chodabwitsa kwambiri cha gawo luteal: kusintha kwa njala. Zowonadi, kupangidwa kwa mahomoni, malinga ndi kafukufuku wina, kumakhudza kalori wambiri panthawiyi. Kutsika munthawi yama follicle, imakulira makamaka gawo loyambirira la ovulation komanso kumapeto kwa luteal gawo. Funso: kupatsidwa mphamvu kwa progesterone ndi estrogen, zomwe zingatanthauze kuchepa kwa serotonin (mahomoni osangalatsa) motero chodabwitsa cha "kulipidwa kwa chakudya" komwe azimayi amakonda mavitamini, calcium ndi magnesium.

Gawo luteal limayang'aniridwa mwapadera kwa azimayi omwe ali ndi vuto lokhala ndi pakati kapena adasokonekera kangapo. Njira yoyamba ndiyo kuyesa kubereka ndikuzindikira vuto la ovulation, makamaka pakuwona momwe kutentha kumakhalira komanso / kapena kuyesa ma hormonal test ndi pelvic ultrasound.

 Ngati mukukayikira kubereka, nthawi zina kukondoweza kwa ovari kungalimbikitsidwe. Zili mkati mwa njira izi zothandizira kubereka (makamaka IVF ndi IVF ICSII) komwe kuthandizira gawo luteal ndikofunikira. Zowonadi, polimbikitsa thumba losunga mazira kuti lipeze mazira ambiri momwe zingathere (asanalandire vitro feteleza), vuto la gawo luteal limayambitsidwa. Matupi achikaso ochulukitsidwa ndi kukondoweza ndiye kuti sangathe kupanga progesterone yokwanira, yomwe imatha kusokoneza kuyika kwa mluza. Chifukwa chake, chithandizo chimayikidwa kuti chilimbikitse kukhalabe ndi pakati. Kenako amakondedwa mamolekyulu awiri:

• progesterone, nthawi zambiri imaperekedwa kumaliseche,
• gonadotropin-release hormone (GnRH) agonists omwe amalimbikitsa kupanga GnRH, mahomoni omwe amalimbikitsa kukula kwa corpus luteum.