Zizindikiro za leptospirosis zimawonekera pakati pa masiku 4 ndi 2 mpaka masabata a 3 mutakumana ndi matendawa. Nthawi zambiri amawoneka ngati chimfine ndi:

kutentha thupi (nthawi zambiri pamwamba pa 39 ° C);

-kuzizira,

- mutu,

- kupweteka kwa minofu, mafupa, m'mimba.

- Kutaya magazi kungathenso kuchitika.

M'mawonekedwe ovuta kwambiri, amatha kuwoneka m'masiku otsatirawa:

- jaundice yodziwika ndi mtundu wachikasu pakhungu ndi azungu amaso;

- kulephera kwa impso,

- kulephera kwa chiwindi,

- kuwonongeka kwa pulmonary,

- matenda a ubongo (meningitis),

- matenda a minyewa (kukomoka, chikomokere).

Mosiyana ndi mitundu yoopsa, palinso mitundu ya matenda popanda zizindikiro.

Ngati kuchira kuli kwanthawi yayitali, nthawi zambiri palibe zotsatilapo kupatula kuthekera kwa zovuta zamaso mochedwa. Komabe, m'mitundu yowopsa, yosathandizidwa kapena kusamalidwa mochedwa, kufa kumaposa 10%.

Nthawi zonse, matendawa amachokera ku zizindikiro zachipatala ndi zizindikiro, kuyezetsa magazi, kapenanso kudzipatula kwa mabakiteriya mu zitsanzo zina.

Matenda atangoyamba kumene, kuzindikira kwa DNA kokha, mwachitsanzo, chibadwa cha mabakiteriya omwe ali m'magazi kapena madzi ena a m'thupi, amatha kudziwa. Kufufuza kwa ma antibodies motsutsana ndi leptospirosis kumakhalabe kuyesa kogwiritsidwa ntchito kwambiri, koma mayeserowa amakhala abwino pakatha sabata, nthawi yomwe thupi limapanga ma antibodies motsutsana ndi mabakiteriyawa komanso kuti akhoza kukhala ochuluka. zokwanira kutheka. Zingakhale zofunikira kubwereza kuyesaku ngati alibe chifukwa adachitidwa mofulumira kwambiri. Kuonjezera apo, chitsimikiziro chovomerezeka cha matendawa chiyenera kupangidwa ndi njira yapadera (mayeso a microagglutination kapena MAT) omwe, ku France, amangochitidwa ndi National reference center for leptospirosis.