LDH imapanga gulu la michere, Lactase dehydrogenases. Amapezeka paliponse m’thupi, kaya m’minofu (komanso mtima), m’minyewa ya m’mapapo kapena m’maselo a magazi. Enzyme ndi puloteni yomwe ntchito yake imakhala yoyambitsa zochitika m'thupi, mwa kuyankhula kwina kuziyambitsa kapena kufulumizitsa ntchito yomwe nthawi zambiri imakhala yochedwa kwambiri.

Pali mitundu ingapo, kapena ma isoenzymes, omwe amadziwika ndi nambala malinga ndi malo awo. Motero awo amtima kapena ubongo amalandira mkhalidwe wa LDH 1 ndi 2, pamene awo a mapulateleti ndi ma lymph nodes ndi LDH3, aja a chiŵindi cha LDH 4 ndi awo a khungu LDH5.

Udindo wa LDH mkati mwa thupi ndikupangitsa kusintha kwa pyruvate kukhala lactate, ndi mosemphanitsa. Ma asidi awiriwa ali ndi gawo la kusamutsa mphamvu pakati pa maselo.

Dziwani kuti imatchedwanso lactate dehydrogenase, kapena lactic dehydrogenase, ndipo nthawi zina imayimiridwa ndi LD.

Chidwi chachipatala cha ma enzymes a LDH ndichoposa zonse kuti azindikire kuwonjezeka kwachilendo pamaso pawo. Nthawi zambiri, LDH imasungidwa m'maselo a thupi. Koma ngati minyewa yawonongeka, imatayika, motero imawonjezera pyruvate kukhala lactate.

Kuwazindikira m'malo enaake kapena kuwunika momwe amachitira m'thupi kungapangitse kuti zitheke kudziwa malo omwe ma cell awonongeka, kapena kuwunika kuopsa kwake. Ndiwothandizanso pakuzindikira matenda osiyanasiyana, kuyambira kuperewera kwa magazi mpaka khansa (onani "Kutanthauzira kwa zotsatira za LDH").

Kuwunika kwa mlingo wa LDH kumachitika ndi kuyesa magazi kosavuta. Mwachindunji, ma laboratories adzasanthula seramu, madzi omwe zigawo za magazi monga maselo ofiira amwazi amasambitsira. Ngakhale kuti omalizawa alinso ndi ma enzymes a LDH m'mitima yawo, ndi pamwamba pa mlingo wonse wa seramu womwe umawerengedwa kuti udziwe ngati mlingowo ndi wachilendo kapena ayi.

Mtengo wowunikira pakuyesa kwa enzyme ya LDH imawunikidwa pa 120 mpaka 246 U / L (mayunitsi pa lita).

Kuti atsatire kafukufukuyu, dokotala akhoza kusanthula zotsatira zoperekedwa ndi labotale, ndipo mwina azindikire zovuta zosiyanasiyana zomwe wodwalayo ali nazo. Nthawi zambiri, padzakhala kofunikira kugwirizanitsa zotsatirazi ndi mlingo wa michere ina kapena ma asidi, chifukwa kuwonjezereka kosavuta kapena kuchepa kwa LDH kungakhale ndi chiyambi chosiyana. Choncho pali mwayi wosiyanasiyana womasulira.

Ngati mulingo wa LDH uli wapamwamba:

• Anemia

Nthawi zambiri imatha kukhala yoyipa (yomwe imatchedwanso Biermer's disease), kapena hemolytic anemia. Potsirizira pake, ma autoantibodies amamatira ku maselo ofiira a magazi ndikuwawononga, zomwe zimawonjezera kuchuluka kwa LDH m'magazi.

• Khansa: Mitundu ina ya khansa monga neoplasias imagwirizanitsidwa ndi kukwera mofulumira kwa LDH.
• Infarction: Pambuyo pa infarction ya myocardial, yokhudzana ndi kuwonongeka kwa minofu ya mtima, kuwonjezeka kwa LDH kumawonedwa mkati mwa maola 10. Mlingowo umatsikanso masabata awiri otsatirawa.
• AVC (tanthauzo lofanana ndi infactus)
• Pancreatitis
• Impso ndi matenda a m'mimba
• Mononucleosis
• Kuphatikizika kwa pulmonary
• angina pectoris
• Mitsempha yotupa
• Chiwindi (choopsa kapena cholepheretsa)
• Myopathy (malingana ndi malo a matendawa)

Ngati mulingo wa LDH ndi wotsika kapena wabwinobwino:

Pamenepa ndikuti palibe vuto lomwe liripo, kapena kudziwika mwa njira iyi, m'thupi.

Osadandaula: Ngakhale kuti mndandanda wa matendawo ukhoza kuopseza anthu omwe ali ndi zotsatira za LDH, ndi bwino kukumbukira kuti zinthu zina zachidule, monga kuchita masewera olimbitsa thupi, zingayambitse LDH kwakanthawi. m’mwazi.

Mosiyana ndi zimenezi, hemolysis (kuphulika kwa maselo ofiira a magazi m'magazi) panthawi yoyesedwa kungayambitse bodza. LDH yomwe ilipo m'maselo ofiira amagazi idzafalikiradi, choncho imasokoneza zotsatira zake.

Pambuyo pofufuza mulingo wa LDH, zotsatira zake zidzatumizidwa kwa dokotala yemwe angakambiranenso nanu ngati kuli kofunikira. Ngati zotsatira zikuwonetsa kukhalapo kwa vuto, ndiye kuti mudzangotumizidwa kwa katswiri yemwe akufunsidwayo.

Pakakhala khansa, kuyang'anitsitsa mlingo wa LDH nthawi zonse kungakhale chizindikiro chosonyeza kuti khansa yakhala yopambana kapena ayi, kuti adziwe ngati maselo omwe akukhudzidwawo akuwonongedwadi kapena akuukira mbali zina za thupi.