Glomerulonephritis ndi matenda a impso zomwe zingakhale ndi magwero osiyanasiyana. Zimakhudza glomeruli, zomwe zimafunikira kuti impso zigwire bwino ntchito. Zimafunika kuyang'aniridwa ndi achipatala chifukwa zingayambitse impso kulephera.

Glomerulonephritis, yomwe nthawi zina imatchedwa nephritis kapena nephrotic syndrome, ndi matenda a glomeruli mu thupi chiuno. Amatchedwanso Malpighi glomerulus, renal glomerulus ndi gawo lofunikira kuti impso zigwire bwino ntchito. Wopangidwa ndi gulu la mitsempha ya magazi, glomerulus imalola kusefa kwa magazi. Njirayi sikuti imangochotsa zinyalala zomwe zimapezeka m'magazi komanso zimasunga bwino mchere ndi madzi m'thupi.

Malingana ndi nthawi ndi kusinthika kwa chikondi, tikhoza kusiyanitsa:

• pachimake glomerulonephritis, zomwe zimawonekera mwadzidzidzi;
• matenda aakulu a glomerulonephritis, zomwe zimakula kwa zaka zingapo.

Tikhozanso kusiyanitsa:

• glomerulonephritis yoyamba, pamene chikondi chimayamba mu impso;
• glomerulonephritis yachiwiri, pamene chikondi ndi chotsatira cha matenda ena.

Kuzindikira kwa glomerulonephritis ndizovuta chifukwa matendawa amatha kukhala ndi zoyambira zambiri:

• chobadwa nacho ;
• zovuta za metabolic ;
• Matenda osokoneza bongomonga systemic lupus (lupus glomerulonephritis) kapena Goodpasture syndrome;
• matenda, monga strep throat (poststreptococcal glomerulonephritis) kapena chiphuphu cha dzino;
• chotupa choopsa.

Pafupifupi 25% ya milandu, glomerulonephritis imatchedwa idiopathic, kutanthauza kuti chifukwa chenicheni sichidziwika.

Glomerulonephritis imafuna chithandizo chamankhwala mwachangu kuti muchepetse zovuta. Ngati palibe chithandizo chamankhwala, matenda a aimpso glomeruli amayambitsa:

• Kusamvana kwa electrolyte, ndi kuchuluka kwa sodium m'thupi, zomwe makamaka zimawonjezera chiopsezo cha matenda a mtima;
• kusunga madzi m'thupi, zomwe zimalimbikitsa kuchitika kwa edema;
• kusagwira bwino ntchito kwa impso, zomwe zingayambitse impso kulephera.

Pamene glomerulonephritis ndi chifukwa cha matenda, akhoza kufalikira kumadera ena a thupi, makamaka mkodzo thirakiti.

Kukula kwa glomerulonephritis kumasiyanasiyana. Zitha kuchitika mwadzidzidzi pachimake glomerulonephritis kapena pang'onopang'ono mu glomerulonephritis. Zizindikiro zimathanso kukhala zosiyana. Glomerulonephritis yosachiritsika imatha kukhala yosaoneka, yopanda zizindikiro, kwa zaka zingapo musanawonetse zizindikiro zoyamba.

Zikawonekera, glomerulonephritis nthawi zambiri imatsagana ndi zochitika zingapo:

• kuchepa pafupipafupi kukodza;
• a hematuria, yodziwika ndi kukhalapo kwa magazi mu mkodzo;
• a mapuloteni, yodziwika ndi kukhalapo kwa mapuloteni mumkodzo, zomwe nthawi zambiri zimabweretsa albuminuria, ndiko kuti, kukhalapo kwa albumin mu mkodzo;
• a oopsa arterial, zomwe zimachitika chifukwa cha kulephera kwa impso;
• un edema, ndani ndi chotsatira china cha kusagwira bwino ntchito kwa impso;
• wa litsipa, zomwe zimatha kutsagana ndi kusapeza bwino;
• wa kupweteka m'mimba, m'njira zovuta kwambiri.

Chithandizo cha glomerulonephritis chimadalira komwe adachokera komanso komwe adachita.

Monga chithandizo choyamba, chithandizo chamankhwala nthawi zambiri chimayikidwa kuti muchepetse zizindikilo ndikuchepetsa zovuta. Katswiri wazachipatala nthawi zambiri amalamula kuti:

• antihypertensives toletsa kuthamanga kwa magazi ndikuchepetsa kuthamanga kwa magazi, chizindikiritso chofala cha glomerulonephritis;
• okodzetsa kuonjezera mkodzo kutulutsa komanso pafupipafupi pokodza.

Mankhwala ena amatha kuperekedwa kuti athetse vuto la glomerulonephritis. Kutengera ndi matendawa, akatswiri azaumoyo akhoza, mwachitsanzo, kupereka:

• maantibayotiki, makamaka pakagwa post-streptococcal glomerulonephritis, kuti athetse matenda impso;
• corticosteroids ndi ma immunosuppressants, makamaka pakakhala lupus glomerulonephritis, kuti achepetse chitetezo chamthupi.

Kuphatikiza pa chithandizo chamankhwala, zakudya zina zimatha kukhazikitsidwa ngati glomerulonephritis. Zakudyazi nthawi zambiri zimatha mu protein ndi sodium, ndipo zimatsagana ndikuwongolera kuchuluka kwamadzi omwe amalowetsedwa.

Ngati chiopsezo cha impso chikule kwambiri, dialysis ingagwiritsidwe ntchito poonetsetsa kuti impso zimagwira ntchito. Mwa mitundu yoopsa kwambiri, kumuika impso kumatha kuganiziridwa.