Mu 1962, wasayansi wa ku America L. Hayflick anasintha gawo la biology ya maselo popanga lingaliro la ma telomeres, omwe amadziwika kuti malire a Hayflick. Malinga ndi Hayflick, nthawi yayitali (yothekera) ya moyo wa munthu ndi zaka zana limodzi ndi makumi awiri - iyi ndi nthawi yomwe maselo ambiri sangathenso kugawanitsa, ndipo zamoyo zimafa.
Njira yomwe michere imakhudza kutalika kwa telomere ndi kudzera mu chakudya chomwe chimakhudza telomerase, puloteni yomwe imawonjezera kubwereza kwa telomeric mpaka kumapeto kwa DNA.
Maphunziro masauzande ambiri aperekedwa ku telomerase. Amadziwika kuti amasunga kukhazikika kwa ma genomic, kuteteza kuyambika kosafunikira kwa njira zowonongeka za DNA, ndikuwongolera ukalamba wa maselo.
Mu 1984, Elizabeth Blackburn, pulofesa wa biochemistry ndi biophysics pa yunivesite ya California ku San Francisco, anapeza kuti pulojekiti ya telomerase inatha kutalikitsa ma telomere mwa kupanga DNA kuchokera ku RNA primer. Mu 2009, Blackburn, Carol Greider, ndi Jack Szostak adalandira Mphotho ya Nobel mu Physiology kapena Medicine pozindikira momwe ma telomeres ndi telomerase ya enzyme imatetezera ma chromosome.
N'zotheka kuti chidziwitso cha ma telomere chidzatipatsa mwayi wowonjezera kwambiri nthawi ya moyo. Mwachibadwa, ochita kafukufuku akupanga mankhwala amtunduwu, koma pali umboni wochuluka wosonyeza kuti moyo wosalira zambiri komanso zakudya zoyenera zimathandizanso.
Izi ndi zabwino, chifukwa ma telomere amfupi ndi owopsa - samatsogolera ku imfa, komanso ku matenda ambiri.
Chifukwa chake, kufupikitsa ma telomere kumalumikizidwa ndi matenda, mndandanda womwe waperekedwa pansipa. Kafukufuku wa zinyama asonyeza kuti matenda ambiri amatha kuthetsedwa mwa kubwezeretsa ntchito ya telomerase. Uku ndikuchepetsa kukana kwa chitetezo chamthupi ku matenda, ndi mtundu wa XNUMX shuga, ndi kuwonongeka kwa atherosclerotic, komanso matenda a neurodegenerative, testicular, splenic, intestinal atrophy.
Kafukufuku wowonjezereka akuwonetsa kuti zakudya zina zimagwira ntchito yofunika kwambiri poteteza kutalika kwa telomere ndipo zimakhudza kwambiri moyo wautali, kuphatikizapo chitsulo, omega-3 mafuta, ndi mavitamini E ndi C, vitamini D3, zinc, vitamini B12.
M'munsimu muli kufotokoza zina mwa zakudya zimenezi.
Astaxanthin
Astaxanthin imakhala ndi anti-inflammatory effect ndipo imateteza bwino DNA. Kafukufuku wasonyeza kuti imatha kuteteza DNA kuti isawonongeke ndi cheza cha gamma. Astaxanthin ili ndi mikhalidwe yambiri yapadera yomwe imapangitsa kuti ikhale yopambana kwambiri.
Mwachitsanzo, ndi oxidizing carotenoid yamphamvu kwambiri yomwe imatha "kutsuka" ma radicals aulere: astaxanthin imakhala yothandiza kwambiri kuwirikiza kawiri kuposa vitamini C, nthawi 65 kuposa beta-carotene, komanso nthawi 54 kuposa vitamini E. Ndi 14 nthawi zogwira mtima kwambiri kuposa vitamini E, komanso nthawi 550 zogwira mtima kwambiri kuposa beta-carotene pochepetsa mpweya wa singlet.
Astaxanthin imadutsa malire a magazi-ubongo ndi magazi-retinal chotchinga (beta-carotene ndi carotenoid lycopene sangathe kuchita izi), kotero kuti ubongo, maso ndi dongosolo lapakati la mitsempha limalandira chitetezo cha antioxidant ndi anti-inflammatory.
Chinthu chinanso chomwe chimasiyanitsa astaxanthin ndi carotenoids ena ndikuti sichingakhale ngati prooxidant. Ma antioxidants ambiri amakhala ngati ma pro-oxidants (mwachitsanzo, amayamba kukhala oxidize m'malo molimbana ndi okosijeni). Komabe, astaxanthin, ngakhale yochulukirapo, sichita ngati wothandizira oxidizing.
Pomaliza, chimodzi mwazinthu zofunika kwambiri za astaxanthin ndi kuthekera kwake kwapadera koteteza selo lonse kuti lisawonongeke: mbali zake zonse zosungunuka m'madzi komanso zosungunuka mafuta. Ma antioxidants ena amakhudza gawo limodzi lokha kapena gawo lina. Makhalidwe apadera a Astaxanthin amalola kuti azikhala mu cell membrane, kuteteza mkati mwa cell.
Gwero labwino kwambiri la astaxanthin ndi alga Haematococcus pluvialis, yomwe imamera kuzilumba za Sweden. Kuphatikiza apo, astaxanthin imakhala ndi ma blueberries akale abwino.
ubiquinol
Ubiquinol ndi mtundu wochepetsedwa wa ubiquinone. M'malo mwake, ubiquinol ndi ubiquinone yomwe yadziphatikiza ndi molekyulu ya haidrojeni yokha. Amapezeka mu broccoli, parsley ndi malalanje.
Zakudya Zosakaniza / Ma Probiotics
N'zoonekeratu kuti zakudya zomwe zimakhala ndi zakudya zosinthidwa zimafupikitsa moyo. Ochita kafukufuku amakhulupirira kuti m'mibadwo yamtsogolo, kusintha kwa ma genetic angapo ndi zovuta zogwira ntchito zomwe zimatsogolera ku matenda ndizotheka - chifukwa chakuti m'badwo wamakono umadya mwachangu zakudya zopangira komanso zokonzedwa.
Chimodzi mwazovuta ndi chakuti zakudya zokonzedwa, zodzaza ndi shuga ndi mankhwala, zimakhala zothandiza kuwononga microflora yamatumbo. Microflora imakhudza chitetezo cha mthupi, chomwe ndi chitetezo chachilengedwe cha thupi. Mankhwala opha tizilombo, kupsinjika maganizo, zotsekemera zopangira, madzi a klorini, ndi zina zambiri zimachepetsanso kuchuluka kwa ma probiotics m'matumbo, omwe amachititsa kuti thupi likhale ndi matenda komanso kukalamba msanga. Moyenera, zakudyazo ziyenera kuphatikizapo zakudya zomwe zimalimidwa kale komanso zofufumitsa.
Vitamini K2
Vitamini iyi ikhoza kukhala "vitamini D ina" monga kafukufuku akuwonetsa kuti vitamini D ili ndi ubwino wambiri wathanzi. Anthu ambiri amapeza vitamini K2 wokwanira (chifukwa amapangidwa ndi thupi m'matumbo aang'ono) kuti magazi asamayende bwino pamlingo wokwanira, koma kuchuluka kumeneku sikokwanira kuteteza thupi ku matenda aakulu. Mwachitsanzo, kafukufuku wazaka zaposachedwapa akusonyeza kuti vitamini K2 ingateteze thupi ku khansa ya prostate. Vitamini K2 ndiwothandizanso paumoyo wamtima. Zokhala mu mkaka, soya (zochuluka - mu natto).
mankhwala enaake a
Magnesium amatenga gawo lofunikira pakubala kwa DNA, kubwezeretsanso komanso kaphatikizidwe ka ribonucleic acid. Kuperewera kwa magnesiamu kwa nthawi yayitali kumabweretsa kufupikitsa ma telomere m'matupi a makoswe komanso chikhalidwe cha ma cell. Kuperewera kwa ayoni a magnesium kumakhudza kwambiri thanzi la majini. Kuperewera kwa magnesium kumachepetsa mphamvu ya thupi yokonza DNA yomwe yawonongeka komanso kumayambitsa zovuta za ma chromosome. Nthawi zambiri, magnesium imakhudza kutalika kwa telomere, chifukwa imalumikizidwa ndi thanzi la DNA komanso kuthekera kwake kudzikonza, ndikuwonjezera kukana kwa thupi kupsinjika kwa okosijeni ndi kutupa. Amapezeka mu sipinachi, katsitsumzukwa, chinangwa cha tirigu, mtedza ndi mbewu, nyemba, maapulo obiriwira ndi letesi, ndi tsabola wokoma.
polyphenols
Ma polyphenols ndi ma antioxidants amphamvu omwe amatha kuchedwetsa ntchitoyi.